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Paul Y.F.

Sports Surgeon 
Knee & Hip Consultant
Regeneration Medicine Doctor  

MBBch, MFSEM (UK), MSc (Sports Med), PhD, FEBOT, FRCS (Tr & Orth) 

Professor Lee specialises in Knee and Hip conditions. Being a double board-certified surgeon with 5 international fellowships, he is able to offer a balanced and up to date opinion between surgery and non-surgical intervention. He has treated UK Premiership footballers with good results and is also at the forefront for cell therapy, being a member of the International Cartilage Regeneration & Joint Preservation Society.

As a Surgeon, Professor Lee offers evidence-based methods with advanced technology to reduce tissue damage and help patients kickstart their recovery.

As a Professor, he is widely published and often invited to give lectures on PRP, Cell therapy, ACL reconstruction, Knee replacement and Hip replacement internationally.


Over the years, Prof Lee has built up a network to exchange knowledge with an international team of surgeons to remain at the cutting edge of innovation.



Prof Lee is a British Regeneration Orthopaedic Surgeon. He is a consultant Orthopaedic Surgeon in the NHS and visiting professor of sports medicine with the School of Sport and Exercise Science, College of Social Science, University of Lincoln. He has a MSc in Sports Medicine and PhD in medical cell engineering and surgical fellowships in regenerative medicine. As an expert in the field of regenerative medicine, Professor Lee is internationally recognised as the ICRS teaching centre of excellence for cartilage and joint preservation surgery.

Combining surgery, technology, engineering and medical principles, Prof Lee has taken medicine to the next level with Single Treatment Autologous Chondrocyte implantation (STACi), Golden Steps Knee Replacement, SPAIRE hip replacement, Same day hip replacement, Tendon saving ACL surgery and regeneration injections.

He regularly performs treatment to bone, joints, cartilage and meniscus with extensive knowledge of the latest biomedical materials and surgical techniques. With his involvement in elite sports[1], Prof Lee has published his results in peer reviewed medical journals on the treatment of muscle injuries[2] in UK Premiership footballers, which has significantly reduced their time for recovery and return to play[3].


As a regional surgical advisor for the Royal College of Surgeons of Edinburgh, Prof Lee fully engages with surgical teaching and offers support to students to develop surgical skills. Prof Lee embraces the use of digital technology, currently working with the school of computer science to build artificial intelligence and deep learning models in musculoskeletal regenerative medicine. As the medical director of MSK Doctors, he has established a network of doctors, surgeons, physios and scientists to form the ENRICH-MSK partnership to promote education and research in MSK regeneration and sports medicine.

Over the past few years, he has achieved many research grants. His research interests range from cartilage research, muscle injuries, Actovegin therapy to digital patient engagement and consent.

Prof Lee is a Key Opinion Leader in Regeneration, Actovegin, Cartilage Cell Therapy, Sports injuries, Joint replacements, General Trauma. His passion for teaching and medical education has led to his involvement with many medical schools, universities, royal colleges and postgraduate teaching organisations internationally. He has also acted as Expert Witness for many medical-legal cases for negligence and personal injuries.

02 Qualifications

Since 2018

Medical  Director

MSK Doctors

The Keep Clinic, MSK House, OPEN MRI

Since 2018

Harley Street Consultant

Harley Street, London Sports Injuries Clinic, London Cartilage Clinic, MSK Doctors

Since 2017

Consultant Orthopaedic Surgeon

NHS England


Health Foundation, Q


Clinical Entrepreneur Fellow, 

Community Member, Quality Improvement 




Trauma and Orthopaedic surgery 




Clinical Leadership Fellow




Royal college of Surgeons of Edinburgh 




(Medical Engineering) Cardiff University 




European Board of Orthopaedic Trauma




(Sports and exercise Medicine) UWIC 




Royal College of surgeons of Edinburgh 


Prince 2






Faculty of Sport and Exercise Medicine UK 




Cardiff University





03 Experience 

Expert in Sports, Trauma and Orthopaedic Surgery
Consultant Orthopaedic surgeon  

Prof Lee founded MSK Doctors, with the aim of advancing musculoskeletal regeneration medicine and offering leading-edge treatment to patients. He has successfully introduced treatments such as STACi, Lipogems, S.P.A.I.R.E. and KneeKG to clinical practice. He is a strong advocate for non-surgical management for knee arthritis and has published his experience with knee brace in the British Medical Journal.

Prof Lee joined the Gilmore Groin Clinic in Harley Street, London and has been working with the late Mr Gilmore's team to treat common groin injuries in athletes. He has introduced a regeneration approach to sports injuries as part of the London Sports & injuries clinic in Harley Street and has treated high profile clients; which has attracted media attention and often consults on topics such as sports injuries, running, knee issues, regeneration and orthopaedics.

Prof Lee partnered with the Phoenix hospital group in Harley Street, London to deliver concierge orthopaedics regeneration and sports surgery to patients. With major investment in the infrastructure and specific protocols, all patients having major surgery such as hip and knee replacement are discharged home within 24 hours, pain-free. Many patients travel internationally for this service which was nominated for the health innovation award in the regeneration surgery network and the concierge award by patient's choice international network.

As MSK Doctors has grown, Prof Lee has become the medical director for MSK Doctors, opening two new dedicated exclusive clinics in Lincolnshire 'the Keep Clinic' and 'MSK house'. He has introduced the only dynamic open MRI scanner in the county to the clinic to benefit the population in rural Lincolnshire.


Perfect surgery relies on knowledge & modern equipment.

Only a few hospitals & clinics can offer this environment for surgeons. 

International Cartilage Regeneration Society - ICRS  

Teaching Centre of Excellence

With a PhD in medical Cell Engineering and surgical fellowships in Regenerative Medicine. Prof Lee is an internationally recognised expert in the field of regenerative medicine, he was awarded ICRS teaching centre of excellence for cartilage and joint preservation surgery.


Combining surgery, technology, engineering and medical principles, he has taken cell therapy to the next level with Single Treatment Autologous Chondrocyte implantation and cell augmented meniscus repair. As the medical director of the London Cartilage Clinic, he regularly performs treatments to cartilage and meniscus with extensive knowledge of the latest biomedical materials and surgical techniques.   

ICRS logo.png
Innovative treatment guided by evidence 

Golden Step Knee Replacement

Cell Augmented - Meniscus Repair

Biological Regeneration Injections

P.R.P. - Platelet Rich Plasma
We should respect biology & apply our knowledge in
Science to Medicine.

Whether it is physio, injections, surgery,  rehab or recovery.

The same principles apply.

The Cells are the same.


Applying biological principles and cell based science to medicine. Giving the body a second chance.

Read More >

Alternative to delay or avoid surgery. Optimise whats there.

Read More >
sports science

Applying sports science and human performance technology to Medicine 

Read More >

Fellowship trained specialist surgeon, double board certified in Trauma and Orthopeadics

Read More >

Professional associations

Fellowship of Royal College of Surgeons (Tr & Orth) 

Membership of Faculty of Sports and Exercise Medicine  

Fellowship European Board of Orthopaedics and Traumatology  

Membership of British Hip Society  

Membership of British Orthopaedic Sports Trauma and Arthroscopy Association  

British Orthopaedic Association 

Biological Knee Society  

International Society Cell and Gene Therapy 

International Cartilage Regeneration Society 


Newspaper Articles

Tennis injuries: The top 5 tennis injuries and how to prevent them

Will doing squats damage your knees?

5 common running myths debunked by the experts

How to avoid shin splints - Why you should NEVER run on pavements

'Leisure sickness': Uncovering the reason why we all get ill on holiday

Why does knee pain get worse in the winter?


Sports Muscle Injuries and Actovegin
ACi Ten Years on
Magic of Fat Cells
Biological Recovery Plan
The Hip Replacement Guide
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Published Medical Journal Articles
by Paul Lee

James Brock, David Golding, Paul M Smith, Len Nokes, Alvin Kwan, Paul Y F Lee, Update on the Role of Actovegin in Musculoskeletal Medicine: A Review of the Past 10 Years. Clinical Journal of Sport Medicine, vol:30 (2020) issue:1 Page83-90. PMID: 31855916; doi:10.1097/JSM.0000000000000566


Ram Rammohan, S Gupta, Paul Y F Lee, Amit Chandratreya. The midterm results of a cohort study of patellofemoral arthroplasty from a non-designer centre using an asymmetric trochlear prosthesis. Knee, Vol:26 (2019) issue: 6 page:1348-1353. doi:10.1016/j.knee.2019.10.026, PMID: 32147094


Ibrahim Haq, Alun D Yewlett, Ashok Marudanayagam, Paul Y F Lee. Lipogems in Osteoarthritis: Fact or Fiction? Journal of Orthopaedics and Trauma, vol. 9 (2019), doi:10.4303/jot/ 236057


Abida Hasan, Alun D Yewlett, Ashok Marudanayagam, Paul Y F Lee,. Key to Success in Anterior Cruciate Ligament Surgery: Pre-Tensioning in the Tape Locking Screw Method, Journal of Orthopaedics and Trauma, vol. 9 (2019), doi:10.4303/jot/ 236058


Sneh Shah, Alun D Yewlett, Ashok Marudanayagam, Paul Y F Lee,. Achilles Tendon Ruptures –Is Operative or Non-Operative Treatment More Effective? Journal of Orthopaedics and Trauma, vol. 9 (2019), doi:10.4303/jot/236055


Alex Calder, Alun D Yewlett, Ashok Marudanayagam, Paul Y F Lee,. Advanced In-Clinic Arthroscopy, the Mi-Eye2. Journal of Orthopaedics and Trauma, vol. 9 (2019), doi:10.4303/jot/236054


Katherine Marino, Rachel Lee and Lee Paul Y F Lee,. Effect of Germanium-Embedded Knee

Sleeve on Osteoarthritis of the Knee. The Orthopaedic Journal of Sports Medicine, Vol:7 (2019), issue:10, DOI: 10.1177/2325967119879124. PMID: 31696136


Alistair Taylor, Paul Y F Lee,. Single Treatment Autologous Chondrocyte Implantation: The Next Generation of ACI. Canadian Journal Biomedical Research & Technology. Journal of Orthopaedics and Trauma, Vol:2 (2019), Issue:2


Paul Y F Lee, David Golding,  Sam Rozewicz, Amit P Chandratreya. Modern synthetic material is a safe and effective alternative for medial patellofemoral ligament reconstruction. Knee Surgery, Sports Traumatology, Arthroscopy. Volume 26 (2018), Page 2716-2712, PMID: 28929187; doi:10.1007/s00167-017-4711-7


Paul Y F Lee, James Brock, Sarah Mansoor and Bethan Whiting. Knee Braces and Anti-Inflammatory Sleeves in Osteoarthritis, Innovation for the 21st Century? Journal of Arthritis

Vol:7(2018) Issue:2. DOI: 10.4172/2167-7921.1000e117


Brock J, Nokes LM, Paul Y F Lee (2018) An update on the role of Actovegin in musculoskeletal medicine. A Review of the Last 10 years. Clinical Journal of Sports Medicine. Clinical Journal of Sport Medicine. 2018 Jan 15. doi: 10.1097/JSM.0000000000000566 

Paul Y F Lee, Chandratreya AP (2017) Modern synthetic material is a safe and effective alternative for medial patellofemoral ligament reconstruction. Knee Surgery, Sports Traumatology, Arthroscopy. doi:10.1007/s00167-017-4711-7.

Paul Y F Lee, Pathi V R Rao, David M Golding, James Brock. Delayed Profunda Femoris Artery Bleeding After Intramedullary Nailing of an Unstable Intertrochanteric Fracture: A Case Report. JBJS Case Connect; Volume 7 (2017) issue: 3; Page: e60; PMID: 29252889; doi:10.2106/JBJS.CC.16.00217

Paul Y F Lee, Rozewicz S, Chandrappa M, Othman A, Jury C Whiting B, (2018) Modern Non- Pharmacological and Non-Surgical Treatments for Hip Pain. Journal of Arthritis. DOI: 10.4172/2167-7921.1000262 

Paul Y F Lee, Murray J, Nixon A, Chandratreya A (2017) Synovial Plica Syndrome of the knee - A commonly overlooked cause of anterior knee pain. The Surgery Journal doi: 10.1055/s- 0037-1598047


Teoh K, Whitham R, Golding D, Wong JF, Paul Y F Lee, Evans AR (2017) R3 Cup Does Not Have a High Failure Rate in Conventional Bearings: A Minimum of 5-Year Follow-Up. Journal of Arthroplasty. doi:10.1016/j.arth.2017.09.059

Paul Y F Lee, Golding D, Woodnutt D (2017) Delayed Profunda Femoris Artery Bleeding After Intramedullary Nailing of an Unstable Intertrochanteric Fracture: A Case Report. JBJS Case Connector doi:10.2106/JBJS.CC.16.00217 

Paul Y F Lee, Charity J, Timperley J (2017) Details of a Tendon–Sparing Posterior Approach in Hemiarthroplasty in the Treatment of Displaced Intracapsular Neck of Femur Fracture. Journal of Arthritis 6: 243. doi:10.4172/2167-7921.1000243

Paul Y F Lee, Golding D, Woodnutt D (2017) The Short Femoral Stem in Total Hip Replacement - A Case Report to Demonstrate an Alternative Solution in Complex Femoral Revision for Prosthetic Implant Fracture. JBJS Case Connector JBJS Case Connector doi: 10.2106/JBJS.CC.16.00174 

Paul Y F Lee, Winfield TG, Harris SRS, et al (2017). Unloading knee brace is a cost-effective method to bridge and delay surgery in unicompartmental knee arthritis. BMJ doi:10.1136/bmjsem- 016- 000195 

Perkins C, Whiting B, Paul Y F Lee (2017) Steroids and Osteoarthritis. Journal of Arthritis 6:e115. doi: 10.4172/2167-7921.1000e115 

Mistry DA, Chandratreya AP, Paul Y F Lee, (2017) A Systematic Review on the Use of Aspirin in the Prevention of Deep Vein Thrombosis in Major Elective Lower Limb Orthopaedic Surgery: An Update from the Past 3 Years. The Surgery Journal. doi: 10.1055/s-0037- 1615817 

Paul Y F Lee, Davies A, Whiting B, Masud S (2017) Consent for Treatment in the UK-2017 Update. Journal of Arthritis 6:e116. doi: 10.4172/2167-7921.1000e116 

Paul Y F Lee, Brock J (2016) Intra-articular Injections for Osteoarthritis: From Bench to Bedside, can we Teach Old Drugs New Tricks?. Journal of Arthritis 5:e111. doi:10.4172/2167- 7921.1000e111 

Brock J, Paul Y F Lee, Woodford C, Robertson A (2016) A Radiological and Clinical Evaluation of Acromioclavicular Joint Reconstruction Using Dog Bone Double Endobutton Technique. Journal of Arthritis 5:207. doi:10.4172/2167-7921.1000207

Man W, Paul Y F Lee, Rogers A (2016) Treatment of Recalcitrant Lateral Epicondylitis with Autologous Conditioning Plasma. Musculoskeletal Disorders and Treatment. 1:1 

Kuiper JH, Paul Y F Lee, Heaton P, Qureshi A and Richardson J (2016) Personalized Medicine for Metal on Metal Hip Resurfacing: Predictors for the 10 Years Success of the Birmingham Hip Resurfacing. Journal of Arthritis 6:1 1-7. doi: 10.4172/2167-7921.1000228 

Paul Y F Lee, Brock J (2016) Modern British Cemented Total Hip Replacement. Journal of Arthritis 5:e113. doi: 10.4172/2167-7921.1000e113 

Paul Y F Lee, Rachala M, Teoh K, Woodnutt D (2016) Long-term results with the Atlas IIIp elastic cementless acetabular component in total hip replacement. International Orthopaedics 40(9), 1835-1842 doi:10.1007/s00264-015-3088-9 

Paul Y F Lee, Alderman P, Roberts P (2016) Polymerizing Bone Cement Can Roughen a Polyethylene Bearing Surface on Total Hip Replacement – A Surface Analysis. Journal of Arthritis 5:203. doi:10.4172/2167-7921.1000203 

Teoh K, Paul Y F Lee, Woodnutt D (2016) Our early experience of the Corin Minihip prosthesis. Hip international 16;26(3):265-9. PMID: 27034100 

Golding D, Paul Y F Lee (2016) Non-surgical and Non-pharmacological Treatment of Knee Pain. J Arthritis 5:225. doi: 10.4172/2167-7921.1000225 

Paul Lee, Holt M (2016) The Effects of Neuromuscular Blocking Agents in Soft Tissue Balancing During Primary Total Knee Arthroplasty. Journal of Arthritis 5:202. doi:10.4172/2167-7921.1000202 

Paul Y F Lee, Gul S, Davies A (2016) Clinical Outcomes of Tibial Tubercle Transfer for Anterior Knee Pain and Patello-femoral Instability. Journal of Arthritis 5:204. doi:10.4172/2167- 7921.1000204 

Man W, Mukherjee A, Paul Lee (2014) The economic impact of individually packaged screws. The Surgeon,12:1, 35-9 PMID: 24012437 

Paul Y F Lee, Evans A (2014) Early Failure of the Polarstem Total Hip Arthroplasty: Can The Australian NJR Tell Us The Full Story? The Journal of Arthroplasty 29:3, 609-11 PMID: 23993433 

Paul Lee, Phillips G, Owen T (2013) Patient positioning for total hip arthroplasty: Can this affect leg length inequality? Welsh Orthopaedic Journal Vol. 1:1, 4-7 

Paul Lee, Robertson A, Lyons K, Forster MC (2013) The MRI appearances for the trufit plug in the treatment of chondral and osteochondral lesions at a minimum of 2 years. Bone and Joint Journal vol. 95-B 

Shahid M, Paul Lee, Evans S, Thomas R (2012) A comparative study of bone shortening and bone loss with use of saw blades versus burr in Hallux Valgus surgery. Foot and Ankle Surgery Vol. 18: 3, 195–197 PMID: 22857962 

Morgan A, Paul Y F Lee, Batra S, and Alderman P (2012) A study assessing whether patients can correctly identify the surgical procedure undergone after hip fracture surgery and the effectiveness of their informed consent Journal of Bone and Joint Surgery (Br) 94-B: 252 

Paul Y F Lee, Nokes L, Smith PM (2012) No effect of intravenous Actovegin on peak aerobic capacity. International Journal of Sports Medicine Vol. 33: 4, 305 – 309 PMID: 22318562 

Paul Y F Lee, Kwan A, Nokes L (2011) Actovegin – Cutting Edge Sports Medicine or “Voodoo” remedy? Current Sports Medicine Reports, Vol. 10:4, 186 – 190 PMID: 2353189 

Paul Y F Lee, Nokes L (2011) Our Experience on Actovegin, is it cutting edge? International Journal of Sports Medicine, Vol. 32 : 4, 237 – 241 PMID: 21271496 




Harley Street